|Load the pic into NeatImage, then click on the DeviceNoiseProfile tab. Since the image was captured in RGB, I'd switch the WorkingColorSpace to RGB.|
Find an area without any important detail - the background to the right of his head is good - now select it by dragging a box. You'll get a warning about the RGB values not being uniform, ignore that - for the best noise profile you want an area without any detail at all, just noise - but there aren't any areas like that in the image.
Now go to the NoiseFilterSettings tab and draw a big box to see the effect of our current filter settings. Not pretty was it? That's due to the non-uniform profile area. It's fixable though! Look at the image again, you'll see that the noise is fine or medium - there aren't many large blotches, so under NoiseReductionAmounts set the Low slider to 0%. Looks a bit better doesn't it? Now play with each of the sliders in turn - try them at 0, wait for it to redraw, then try at 100. Now you know what the slider does - try finding the optimal value for it :)
Load back into Photoshop on top of the original image - turn the Layer on and off to see what effect we've had. In this case the results were mostly positive, except for a bit of detail lost around the edges - so use a soft-edged eraser to knock that out.
Finally SmartSharpen 75%, 0.8px, 0 to bring out the fine detail :)
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